6AXA
Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with (3S)-5-fluoro-3-hydroxy-1,3-dihydroindol-2-one
Summary for 6AXA
Entry DOI | 10.2210/pdb6axa/pdb |
Related | 5CXQ |
Descriptor | Purine nucleoside phosphorylase, DIMETHYL SULFOXIDE, (3S)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, transferase |
Biological source | Schistosoma mansoni (Blood fluke) |
Total number of polymer chains | 1 |
Total formula weight | 32227.67 |
Authors | Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G. (deposition date: 2017-09-06, release date: 2018-09-12, Last modification date: 2023-10-04) |
Primary citation | Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G. Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-3-hydroxy-1,3-dihydroindol-2-one To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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