6AVS

Complex structure of JMJD5 and Symmetric Monomethyl-Arginine (MMA)

Summary for 6AVS

• Entry DOI: 10.2210/pdb6avs/pdb
• Descriptor: Lysine-specific demethylase 8, ZINC ION, (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, ... (4 entities in total)
• Functional Keywords: demethylase, jumonji, histone, endopeptidase, exopeptidase, oxidoreductase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q8N371
• Total number of polymer chains: 1
• Total formula weight: 27542.53

Authors

Lee, S.,Liu, H.,Wang, Y.,Dai, S.,Zhang, G. (deposition date: 2017-09-04, release date: 2018-02-28, Last modification date: 2023-10-04)

• Primary citation: Liu, H.,Wang, C.,Lee, S.,Ning, F.,Wang, Y.,Zhang, Q.,Chen, Z.,Zang, J.,Nix, J.,Dai, S.,Marrack, P.,Hagman, J.,Kappler, J.,Zhang, G.; Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.; Sci Rep, 8:3275-3275, 2018; PubMed: 29459673; DOI: 10.1038/s41598-018-21432-8

Experimental method

X-RAY DIFFRACTION (2.02 Å)