6AVS

Complex structure of JMJD5 and Symmetric Monomethyl-Arginine (MMA)

6AVS の概要

分子名称Lysine-specific demethylase 8, ZINC ION, (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, ... (4 entities in total)
機能のキーワードdemethylase, jumonji, histone, endopeptidase, exopeptidase, oxidoreductase
由来する生物種Homo sapiens (Human)
細胞内の位置Nucleus  Q8N371
ポリマー鎖数1
分子量合計27542.54
構造登録者
Lee, S.,Liu, H.,Wang, Y.,Dai, S.,Zhang, G. (登録日: 2017-09-04, 公開日: 2018-02-28, 最終更新日: 2018-03-07)
主引用文献
Liu, H.,Wang, C.,Lee, S.,Ning, F.,Wang, Y.,Zhang, Q.,Chen, Z.,Zang, J.,Nix, J.,Dai, S.,Marrack, P.,Hagman, J.,Kappler, J.,Zhang, G.
Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8:3275-3275, 2018
PubMed: 29459673 (主引用文献が同じPDBエントリー)
DOI: 10.1038/s41598-018-21432-8
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.02 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274130.4%1.6%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード