6AS6

Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 3-Prop-6-Me-phenyldiketoacid

Summary for 6AS6

Entry DOI	10.2210/pdb6as6/pdb
Related	6ASU 6AU9
Descriptor	Malate synthase G, MAGNESIUM ION, (2Z)-4-(5-cyclopropyl-2-methylphenyl)-2-hydroxy-4-oxobut-2-enoic acid, ... (5 entities in total)
Functional Keywords	acetyltransferase, structural genomics, tb structural genomics consortium, tbsgc, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	80857.72
Authors	Krieger, I.V.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2017-08-23, release date: 2018-08-29, Last modification date: 2023-10-04)
Primary citation	Ellenbarger, J.F.,Krieger, I.V.,Huang, H.L.,Gomez-Coca, S.,Ioerger, T.R.,Sacchettini, J.C.,Wheeler, S.E.,Dunbar, K.R. Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58:2085-2091, 2018 Cited by PubMed: 30137983 DOI: 10.1021/acs.jcim.8b00417 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation