6ARO

F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with 8-hydroxyquinoline beta-galactoside

Summary for 6ARO

Entry DOI	10.2210/pdb6aro/pdb
Descriptor	F9 pilus adhesin FmlH, 8-hydroxyquinoline beta-galactopyranoside, SULFATE ION, ... (4 entities in total)
Functional Keywords	fimbrial adhesin, lectin, bacterial adhesion, sugar binding protein
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	36550.84
Authors	Kalas, V.,Hultgren, S.J. (deposition date: 2017-08-23, release date: 2018-02-28, Last modification date: 2023-10-04)
Primary citation	Kalas, V.,Hibbing, M.E.,Maddirala, A.R.,Chugani, R.,Pinkner, J.S.,Mydock-McGrane, L.K.,Conover, M.S.,Janetka, J.W.,Hultgren, S.J. Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115:E2819-E2828, 2018 Cited by PubMed: 29507247 DOI: 10.1073/pnas.1720140115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation