6AOY

F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG)

6AOY の概要

• エントリーDOI: 10.2210/pdb6aoy/pdb
• 分子名称: Fml fimbrial adhesin FmlD, SULFATE ION, 2-nitrophenyl beta-D-galactopyranoside, ... (4 entities in total)
• 機能のキーワード: fimbrial adhesin, lectin, bacterial adhesion, sugar binding protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36237.49

構造登録者

Kalas, V.,Hultgren, S.J. (登録日: 2017-08-16, 公開日: 2018-02-28, 最終更新日: 2023-10-04)

• 主引用文献: Kalas, V.,Hibbing, M.E.,Maddirala, A.R.,Chugani, R.,Pinkner, J.S.,Mydock-McGrane, L.K.,Conover, M.S.,Janetka, J.W.,Hultgren, S.J.; Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.; Proc.Natl.Acad.Sci.USA, 115:E2819-E2828, 2018; PubMed: 29507247; DOI: 10.1073/pnas.1720140115

実験手法

X-RAY DIFFRACTION (1.8 Å)