6ALS

Solution structure of a DNA dodecamer with 5-methylcytosine at the 3rd and 9th position and 8-oxoguanine at the 4th position

6ALS の概要

• エントリーDOI: 10.2210/pdb6als/pdb
• NMR情報: BMRB: 30328
• 分子名称: DNA (5'-D(*(DC5)P*GP*(DMC)P*(8OG)P*AP*AP*TP*TP*(DMC)P*GP*CP*(DG3))-3') (1 entity in total)
• 機能のキーワード: drew-dickerson, dna, non-canonical, modified dna, oxidized dna, dna damage, dna adduct, lesion
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7254.93

構造登録者

Gruber, D.R.,Shernyukov, A.V.,Endutkin, A.V.,Bagryanskaya, E.G.,Zharkov, D.O.,Smirnov, S.L. (登録日: 2017-08-08, 公開日: 2017-09-06, 最終更新日: 2024-05-01)

• 主引用文献: Gruber, D.R.,Toner, J.J.,Miears, H.L.,Shernyukov, A.V.,Kiryutin, A.S.,Lomzov, A.A.,Endutkin, A.V.,Grin, I.R.,Petrova, D.V.,Kupryushkin, M.S.,Yurkovskaya, A.V.,Johnson, E.C.,Okon, M.,Bagryanskaya, E.G.,Zharkov, D.O.,Smirnov, S.L.; Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation.; Nucleic Acids Res., 46:10827-10839, 2018; PubMed: 30289469; DOI: 10.1093/nar/gky893

実験手法