6AKX
The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 21
Summary for 6AKX
Entry DOI | 10.2210/pdb6akx/pdb |
Descriptor | C-C chemokine receptor type 5,Rubredoxin,C-C chemokine receptor type 5, ZINC ION, NITRATE ION, ... (5 entities in total) |
Functional Keywords | g protein-coupled receptor chemokine receptor ccr5 antagonist complex structure, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 88946.65 |
Authors | |
Primary citation | Peng, P.,Chen, H.,Zhu, Y.,Wang, Z.,Li, J.,Luo, R.H.,Wang, J.,Chen, L.,Yang, L.M.,Jiang, H.,Xie, X.,Wu, B.,Zheng, Y.T.,Liu, H. Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists. J. Med. Chem., 61:9621-9636, 2018 Cited by PubMed: 30234300DOI: 10.1021/acs.jmedchem.8b01077 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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