6AIK

Cab2 mutant H337A complex with phosphopantothenoyl-CMP

6AIK の概要

• エントリーDOI: 10.2210/pdb6aik/pdb
• 分子名称: Phosphopantothenate--cysteine ligase CAB2, PHOSPHORIC ACID MONO-[3-(3-{[5-(4-AMINO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4- DIHYDROXY-TETRAHYDRO-FURAN-2- YLMETHOXY]-HYDROXY-PHOSPHORYLOXY}-3-OXO-PROPYLCARBAMOYL)-3-HYDROXY-2,2- DIMETHYL-PROPYL] ESTER (3 entities in total)
• 機能のキーワード: phosphopantothenate--cysteine ligase, complex, phosphopantothenoyl-cmp, ligase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86578.11

構造登録者

Zheng, P.,Zhu, Z. (登録日: 2018-08-24, 公開日: 2019-03-20, 最終更新日: 2023-11-22)

• 主引用文献: Zheng, P.,Zhang, M.,Khan, M.H.,Liu, H.,Jin, Y.,Yue, J.,Gao, Y.,Teng, M.,Zhu, Z.,Niu, L.; Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.; J. Mol. Biol., 431:764-776, 2019; PubMed: 30653991; DOI: 10.1016/j.jmb.2019.01.012

実験手法

X-RAY DIFFRACTION (1.83 Å)