6AHE
Crystal structure of enoyl-ACP reductase from Acinetobacter baumannii in complex with NAD and AFN-1252
6AHE の概要
エントリーDOI | 10.2210/pdb6ahe/pdb |
分子名称 | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide, ... (4 entities in total) |
機能のキーワード | fabi, acinetobacter baumannii, nad, afn-1252, inhibitor complex, oxidoreductase |
由来する生物種 | Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 (Acinetobacter baumannii ATCC 19606) |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 118806.43 |
構造登録者 | Rani, S.T.,Nataraj, V.,Laxminarasimhan, A.,Thomas, A.,Krishnamurthy, N. (登録日: 2018-08-17, 公開日: 2019-08-21, 最終更新日: 2023-11-22) |
主引用文献 | Rao, N.K.,Nataraj, V.,Ravi, M.,Panchariya, L.,Palai, K.,Talapati, S.R.,Lakshminarasimhan, A.,Ramachandra, M.,Antony, T. Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies. Chem.Biol.Drug Des., 96:704-713, 2020 Cited by PubMed: 32227402DOI: 10.1111/cbdd.13686 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.29 Å) |
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