Structure of Rac1 in the low-affinity state for Mg2+

Summary for 6AGP

DescriptorRas-related C3 botulinum toxin substrate 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywordsnucleotide binding, gtpase activity, gtp binding, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight20499.84
Toyama, Y.,Kontani, K.,Katada, T.,Shimada, I. (deposition date: 2018-08-13, release date: 2019-03-20)
Primary citation
Toyama, Y.,Kontani, K.,Katada, T.,Shimada, I.
Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR
Sci Adv, 5:eaav8945-eaav8945, 2019
DOI: 10.1126/sciadv.aav8945
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers3 0.9% 4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures