6A94

Crystal structure of 5-HT2AR in complex with zotepine

6A94 の概要

• エントリーDOI: 10.2210/pdb6a94/pdb
• 分子名称: 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, 2-(3-chloranylbenzo[b][1]benzothiepin-5-yl)oxy-N,N-dimethyl-ethanamine, CHOLESTEROL, ... (7 entities in total)
• 機能のキーワード: receptor, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86215.78

構造登録者

Kimura, T.K.,Asada, H.,Inoue, A.,Kadji, F.M.N.,Im, D.,Mori, C.,Arakawa, T.,Hirata, K.,Nomura, Y.,Nomura, N.,Aoki, J.,Iwata, S.,Shimamura, T. (登録日: 2018-07-11, 公開日: 2019-02-13, 最終更新日: 2023-11-22)

• 主引用文献: Kimura, K.T.,Asada, H.,Inoue, A.,Kadji, F.M.N.,Im, D.,Mori, C.,Arakawa, T.,Hirata, K.,Nomura, Y.,Nomura, N.,Aoki, J.,Iwata, S.,Shimamura, T.; Structures of the 5-HT2Areceptor in complex with the antipsychotics risperidone and zotepine.; Nat.Struct.Mol.Biol., 26:121-128, 2019; PubMed: 30723326; DOI: 10.1038/s41594-018-0180-z

実験手法

X-RAY DIFFRACTION (2.9 Å)