6A8G

The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5

6A8G の概要

• エントリーDOI: 10.2210/pdb6a8g/pdb
• 分子名称: muPAin-1-IG, Urokinase-type plasminogen activator chain B, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: peptides inhibitor, mupa, serine protease, hydrolase, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 57897.91

構造登録者

Wang, D.,Yang, Y.S.,Jiang, L.G.,Huang, M.D.,Li, J.Y.,Andreasen, P.A.,Xu, P.,Chen, Z. (登録日: 2018-07-08, 公開日: 2019-02-20, 最終更新日: 2023-11-22)

• 主引用文献: Wang, D.,Yang, Y.,Jiang, L.,Wang, Y.,Li, J.,Andreasen, P.A.,Chen, Z.,Huang, M.,Xu, P.; Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.; J.Med.Chem., 62:2172-2183, 2019; PubMed: 30707839; DOI: 10.1021/acs.jmedchem.8b01908

実験手法

X-RAY DIFFRACTION (2.53 Å)