6A4O

HEWL crystals soaked in 2.5M GuHCl for 20 minutes

Replaces:  5H6C

Summary for 6A4O

• Entry DOI: 10.2210/pdb6a4o/pdb
• Descriptor: Lysozyme C, GUANIDINE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: protein unfolding, chemical denaturant, guanidine, lysozyme, hydrolase
• Biological source: Gallus gallus (Chicken)
• Total number of polymer chains: 1
• Total formula weight: 14884.03

Authors

Tushar, R.,Kini, R.M.,Koh, C.Y.,Hosur, M.V. (deposition date: 2018-06-20, release date: 2019-03-13, Last modification date: 2023-11-22)

• Primary citation: Raskar, T.,Koh, C.Y.,Niebling, S.,Kini, R.M.,Hosur, M.V.; X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.; Int. J. Biol. Macromol., 122:903-913, 2019; PubMed: 30412756; DOI: 10.1016/j.ijbiomac.2018.11.023

Experimental method

X-RAY DIFFRACTION (1.75 Å)