6A21

Mandelate oxidase mutant-Y128F with the N5-malonyl-FMN adduct

Summary for 6A21

• Entry DOI: 10.2210/pdb6a21/pdb
• Descriptor: 4-hydroxymandelate oxidase, 3-[7,8-dimethyl-2,4-bis(oxidanylidene)-10-[(2S,3S,4R)-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentyl]-1H-benzo[g]pteridin-5-yl]-3-oxidanylidene-propanoic acid (3 entities in total)
• Functional Keywords: fmn-dependent oxidase, flavoprotein
• Biological source: Amycolatopsis orientalis (Nocardia orientalis)
• Total number of polymer chains: 1
• Total formula weight: 40573.97

Authors

Li, T.L.,Lin, K.H. (deposition date: 2018-06-08, release date: 2019-06-19, Last modification date: 2023-11-22)

• Primary citation: Lyu, S.Y.,Lin, K.H.,Yeh, H.W.,Li, Y.S.,Huang, C.M.,Wang, Y.L.,Shih, H.W.,Hsu, N.S.,Wu, C.J.,Li, T.L.; The flavin mononucleotide cofactor in alpha-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level.; Acta Crystallogr D Struct Biol, 75:918-929, 2019; PubMed: 31588923; DOI: 10.1107/S2059798319011938

Experimental method

X-RAY DIFFRACTION (1.501 Å)