6A1Q

Crystal structures of disordered Z-type helices

Summary for 6A1Q

• Entry DOI: 10.2210/pdb6a1q/pdb
• Related: 6A1O
• Descriptor: DNA (5'-D(P*TP*GP*TP*G)-3'), DNA (5'-D(P*CP*AP*CP*A)-3') (3 entities in total)
• Functional Keywords: tetradecamer sequence, alternate pyr-pur repeat, left handed z-dna duplex, discontinuous helices, p3(2), dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 7144.98

Authors

Karthik, S.,Mandal, P.K.,Thirugnanasambandam, A.,Gautham, N. (deposition date: 2018-06-07, release date: 2019-01-16, Last modification date: 2023-11-22)

Primary citation

Karthik, S.,Mandal, P.K.,Thirugnanasambandam, A.,Gautham, N.
Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38:279-293, 2019

PubMed Abstract: The X-ray crystal structures of a decamer sequence d(CGCGTACGCG) and a tetradecamer sequence d(CGCGCGTACGCGCG) are presented here. Both sequences are alternating pyrimidine-purine repeat sequences and they form disordered, pseudo-continuous left handed Z-type helices. They demonstrate interesting variants of the 'bundles of columns of helices' mode of packing.

PubMed: 30588873
DOI: 10.1080/15257770.2018.1517883

Experimental method

X-RAY DIFFRACTION (2.501 Å)