6A03

Structure of pSTING complex

Summary for 6A03

Entry DOI	10.2210/pdb6a03/pdb
Descriptor	Stimulator of interferon genes protein, SULFATE ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ... (4 entities in total)
Functional Keywords	psting, signaling protein
Biological source	Sus scrofa (Pig)
Total number of polymer chains	2
Total formula weight	46422.00
Authors	Yuan, Z.L.,Shang, G.J.,Cong, X.Y.,Gu, L.C. (deposition date: 2018-06-05, release date: 2019-06-19, Last modification date: 2024-03-27)
Primary citation	Cong, X.,Yuan, Z.,Du, Y.,Wu, B.,Lu, D.,Wu, X.,Zhang, Y.,Li, F.,Wei, B.,Li, J.,Wu, J.,Xu, S.,Wang, J.,Qi, J.,Shang, G.,Gu, L. Crystal structures of porcine STINGCBD-CDN complexes reveal the mechanism of ligand recognition and discrimination of STING proteins. J.Biol.Chem., 294:11420-11432, 2019 Cited by PubMed: 31167783 DOI: 10.1074/jbc.RA119.007367 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.597 Å)

Structure validation