5ZXK

Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP

Summary for 5ZXK

• Entry DOI: 10.2210/pdb5zxk/pdb
• Descriptor: Butyrophilin subfamily 3 member A1, (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate (3 entities in total)
• Functional Keywords: substrate binding, agonist, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 22923.87

Authors

Yang, Y.Y.,Liu, W.D.,Chen, C.C.,Guo, R.T.,Zhang, Y.H. (deposition date: 2018-05-21, release date: 2019-04-03, Last modification date: 2023-11-22)

• Primary citation: Yang, Y.,Li, L.,Yuan, L.,Zhou, X.,Duan, J.,Xiao, H.,Cai, N.,Han, S.,Ma, X.,Liu, W.,Chen, C.C.,Wang, L.,Li, X.,Chen, J.,Kang, N.,Chen, J.,Shen, Z.,Malwal, S.R.,Liu, W.,Shi, Y.,Oldfield, E.,Guo, R.T.,Zhang, Y.; A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.; Immunity, 50:1043-, 2019; PubMed: 30902636; DOI: 10.1016/j.immuni.2019.02.016

Experimental method

X-RAY DIFFRACTION (1.96 Å)