5ZTE

Crystal structure of PrxA C119S mutant from Arabidopsis thaliana

Summary for 5ZTE

• Entry DOI: 10.2210/pdb5zte/pdb
• Descriptor: 2-Cys peroxiredoxin BAS1, chloroplastic (2 entities in total)
• Functional Keywords: arabidopsis thaliana; redox regulation; chloroplast thioredoxin systems; oxidative and photo-oxidative stress., oxidoreductase
• Biological source: Arabidopsis thaliana (Mouse-ear cress)
• Total number of polymer chains: 10
• Total formula weight: 229059.67

Authors

Yang, Y.,Cai, W.,Wang, J.,Pan, W.,Liu, L.,Wang, M.,Zhang, M. (deposition date: 2018-05-03, release date: 2018-10-10, Last modification date: 2023-11-22)

Primary citation

Yang, Y.,Cai, W.,Wang, J.,Pan, W.,Liu, L.,Wang, M.,Zhang, M.
Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74:625-631, 2018

PubMed Abstract: Peroxiredoxins (Prxs), a large family of antioxidant enzymes, are abundant in all living organisms. Peroxiredoxin A (PrxA) from Arabidopsis thaliana belongs to the typical 2-Cys Prx family and is localized in the chloroplast. This article reports the crystal structure of a PrxA C119S mutant refined to 2.6 Å resolution. The protein exists as a decamer both in the crystal structure and in solution. The structure is in the reduced state suitable for the approach of peroxide, though conformational changes are needed for the resolving process.

PubMed: 30279313
DOI: 10.1107/S2053230X18010920

Experimental method

X-RAY DIFFRACTION (2.6 Å)