5ZTE

Crystal structure of PrxA C119S mutant from Arabidopsis thaliana

5ZTE の概要

• エントリーDOI: 10.2210/pdb5zte/pdb
• 分子名称: 2-Cys peroxiredoxin BAS1, chloroplastic (2 entities in total)
• 機能のキーワード: arabidopsis thaliana; redox regulation; chloroplast thioredoxin systems; oxidative and photo-oxidative stress., oxidoreductase
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 229059.67

構造登録者

Yang, Y.,Cai, W.,Wang, J.,Pan, W.,Liu, L.,Wang, M.,Zhang, M. (登録日: 2018-05-03, 公開日: 2018-10-10, 最終更新日: 2023-11-22)

主引用文献

Yang, Y.,Cai, W.,Wang, J.,Pan, W.,Liu, L.,Wang, M.,Zhang, M.
Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74:625-631, 2018

PubMed Abstract: Peroxiredoxins (Prxs), a large family of antioxidant enzymes, are abundant in all living organisms. Peroxiredoxin A (PrxA) from Arabidopsis thaliana belongs to the typical 2-Cys Prx family and is localized in the chloroplast. This article reports the crystal structure of a PrxA C119S mutant refined to 2.6 Å resolution. The protein exists as a decamer both in the crystal structure and in solution. The structure is in the reduced state suitable for the approach of peroxide, though conformational changes are needed for the resolving process.

PubMed: 30279313
DOI: 10.1107/S2053230X18010920

実験手法

X-RAY DIFFRACTION (2.6 Å)