5ZSL

Crystal structure of monkey TLR7 in complex with GGUUGG

5ZSL の概要

• エントリーDOI: 10.2210/pdb5zsl/pdb
• 分子名称: Toll-like receptor 7, RNA (5'-R(P*UP*UP*GP*A)-3'), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: innate immunity toll-like receptors, immune system
• 由来する生物種: Macaca mulatta (Rhesus macaque); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 198849.33

構造登録者

Zhang, Z.,Ohto, U.,Shimizu, T. (登録日: 2018-04-28, 公開日: 2019-01-30, 最終更新日: 2024-03-13)

• 主引用文献: Zhang, Z.,Ohto, U.,Shibata, T.,Taoka, M.,Yamauchi, Y.,Sato, R.,Shukla, N.M.,David, S.A.,Isobe, T.,Miyake, K.,Shimizu, T.; Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.; Cell Rep, 25:3371-3381.e5, 2018; PubMed: 30566863; DOI: 10.1016/j.celrep.2018.11.081

実験手法

X-RAY DIFFRACTION (2.3 Å)