5ZO7
Kinesin spindle protein Eg5 in complex with STLC-type inhibitor PVEI0138
Summary for 5ZO7
Entry DOI | 10.2210/pdb5zo7/pdb |
Descriptor | Kinesin-like protein KIF11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | motor domain, atp binding, cell cycle |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 84536.03 |
Authors | Yokoyama, H.,Sato, K. (deposition date: 2018-04-12, release date: 2018-10-10, Last modification date: 2024-03-27) |
Primary citation | Yokoyama, H.,Sawada, J.I.,Sato, K.,Ogo, N.,Kamei, N.,Ishikawa, Y.,Hara, K.,Asai, A.,Hashimoto, H. Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors. Acs Omega, 3:12284-12294, 2018 Cited by PubMed: 31459302DOI: 10.1021/acsomega.8b00778 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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