5ZO7

Kinesin spindle protein Eg5 in complex with STLC-type inhibitor PVEI0138

Summary for 5ZO7

• Entry DOI: 10.2210/pdb5zo7/pdb
• Descriptor: Kinesin-like protein KIF11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: motor domain, atp binding, cell cycle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 84536.03

Authors

Yokoyama, H.,Sato, K. (deposition date: 2018-04-12, release date: 2018-10-10, Last modification date: 2024-03-27)

• Primary citation: Yokoyama, H.,Sawada, J.I.,Sato, K.,Ogo, N.,Kamei, N.,Ishikawa, Y.,Hara, K.,Asai, A.,Hashimoto, H.; Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.; Acs Omega, 3:12284-12294, 2018; PubMed: 31459302; DOI: 10.1021/acsomega.8b00778

Experimental method

X-RAY DIFFRACTION (2.6 Å)