5ZO6
Crystal structure of C166, a backbone circularized G-CSF
Summary for 5ZO6
| Entry DOI | 10.2210/pdb5zo6/pdb |
| Descriptor | Granulocyte colony-stimulating factor (2 entities in total) |
| Functional Keywords | cytokine, four-helix bundle, back-bone circularization |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 17893.60 |
| Authors | Shibuya, R.,Miyafusa, T.,Honda, S. (deposition date: 2018-04-12, release date: 2019-04-17, Last modification date: 2023-11-22) |
| Primary citation | Shibuya, R.,Miyafusa, T.,Honda, S. Stabilization of backbone-circularized protein is attained by synergistic gains in enthalpy of folded structure and entropy of unfolded structure. Febs J., 2019 Cited by PubMed: 31605655DOI: 10.1111/febs.15092 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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