5ZNI
Plasmodium falciparum purine nucleoside phosphorylase in complex with mefloquine
Summary for 5ZNI
| Entry DOI | 10.2210/pdb5zni/pdb |
| Descriptor | Purine nucleoside phosphorylase, PHOSPHATE ION, Mefloquine, ... (4 entities in total) |
| Functional Keywords | transferase, nucleoside phosphorylase |
| Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
| Total number of polymer chains | 1 |
| Total formula weight | 27364.44 |
| Authors | Chen, D.,Nordlund, P.,Dziekan, J.M. (deposition date: 2018-04-09, release date: 2019-01-16, Last modification date: 2023-11-22) |
| Primary citation | Dziekan, J.M.,Yu, H.,Chen, D.,Dai, L.,Wirjanata, G.,Larsson, A.,Prabhu, N.,Sobota, R.M.,Bozdech, Z.,Nordlund, P. Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay. Sci Transl Med, 11:-, 2019 Cited by PubMed: 30602534DOI: 10.1126/scitranslmed.aau3174 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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