Plasmodium falciparum purine nucleoside phosphorylase in complex with mefloquine

Summary for 5ZNI

DescriptorPurine nucleoside phosphorylase, PHOSPHATE ION, Mefloquine, ... (4 entities in total)
Functional Keywordstransferase, nucleoside phosphorylase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains1
Total molecular weight27364.44
Chen, D.,Nordlund, P.,Dziekan, J.M. (deposition date: 2018-04-09, release date: 2019-01-16)
Primary citation
Dziekan, J.M.,Yu, H.,Chen, D.,Dai, L.,Wirjanata, G.,Larsson, A.,Prabhu, N.,Sobota, R.M.,Bozdech, Z.,Nordlund, P.
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.
Sci Transl Med, 11:-, 2019
PubMed: 30602534 (PDB entries with the same primary citation)
DOI: 10.1126/scitranslmed.aau3174
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25520 3.6% 3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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