5ZMU

Crystal structure of a cis-epoxysuccinate hydrolase producing D(-)-tartaric acids

5ZMU の概要

• エントリーDOI: 10.2210/pdb5zmu/pdb
• 分子名称: Cis-epoxysuccinate hydrolase, ZINC ION (3 entities in total)
• 機能のキーワード: zn-binding, tim-barrel, hydrolase
• 由来する生物種: Bordetella sp. BK-52
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 139030.18

構造登録者

Dong, S.,Liu, X.,Wang, X.,Feng, Y. (登録日: 2018-04-06, 公開日: 2018-08-08, 最終更新日: 2023-11-22)

主引用文献

Dong, S.,Liu, X.,Cui, G.Z.,Cui, Q.,Wang, X.,Feng, Y.
Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid.
Chem. Commun. (Camb.), 54:8482-8485, 2018

PubMed Abstract: Crystal structure determination and mutagenesis analysis of a cis-epoxysuccinate hydrolase which produces enantiomerically pure d(-)-tartaric acids revealed a zinc ion and essential residues in the stereoselective mechanism for the catalytic reaction of the small mirror symmetric substrate.

PubMed: 30003205
DOI: 10.1039/c8cc04398a

実験手法

X-RAY DIFFRACTION (1.5 Å)