5ZJZ

Stapled-peptides tailored against initiation of translation

5ZJZ の概要

• エントリーDOI: 10.2210/pdb5zjz/pdb
• 分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4 gamma 1, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: cap dependent translation, rna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24636.81

構造登録者

Lama, D.,Liberator, A.,Frosi, Y.,Nakhle, J.,Tsomia, N.,Bashir, T.,Lane, D.P.,Brown, C.J.,Verma, C.S.,Auvin, S.,Ciesielski, F.,Uhring, M. (登録日: 2018-03-22, 公開日: 2019-02-20, 最終更新日: 2023-11-22)

• 主引用文献: Lama, D.,Liberatore, A.M.,Frosi, Y.,Nakhle, J.,Tsomaia, N.,Bashir, T.,Lane, D.P.,Brown, C.J.,Verma, C.S.,Auvin, S.; Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein.; Chem Sci, 10:2489-2500, 2019; PubMed: 30881679; DOI: 10.1039/c8sc03759k

実験手法

X-RAY DIFFRACTION (1.67 Å)