5ZJ2
Crystal structure of NDM-1 in complex with D-captopril
Summary for 5ZJ2
Entry DOI | 10.2210/pdb5zj2/pdb |
Related | 5ZIO 5ZJ1 |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, ... (4 entities in total) |
Functional Keywords | ndm-1, metallo-beta-lactamase, antibiotic resistent, inhibitor, thio compounds, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 25979.92 |
Authors | |
Primary citation | Ma, G.,Wang, S.,Wu, K.,Zhang, W.,Ahmad, A.,Hao, Q.,Lei, X.,Zhang, H. Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors Bioorg.Med.Chem., 29:-, 2020 Cited by DOI: 10.1016/j.bmc.2020.115902PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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