5ZIT
Crystal structure of human Enterovirus D68 RdRp in complex with NADPH
Summary for 5ZIT
| Entry DOI | 10.2210/pdb5zit/pdb |
| Descriptor | RdRp, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
| Functional Keywords | evd68-rdrp, complex, inhibitor, nadph-na4, structure-based design, rna binding protein |
| Biological source | Enterovirus D68 |
| Total number of polymer chains | 1 |
| Total formula weight | 52764.80 |
| Authors | Wang, M.L.,Li, L.,Chen, Y.P.,Jiang, H.,Zhang, Y.,Su, D. (deposition date: 2018-03-17, release date: 2019-04-17, Last modification date: 2023-11-22) |
| Primary citation | Li, L.,Wang, M.,Chen, Y.,Hu, T.,Yang, Y.,Zhang, Y.,Bi, G.,Wang, W.,Liu, E.,Han, J.,Lu, T.,Su, D. Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., :107510-107510, 2020 Cited by PubMed: 32353513DOI: 10.1016/j.jsb.2020.107510 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.196 Å) |
Structure validation
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