5ZGX
Crystal structure of NDM-1 at pH7.5 (Succinate) with 1 molecule per asymmetric unit
Summary for 5ZGX
Entry DOI | 10.2210/pdb5zgx/pdb |
Related | 5XP6 5ZGI 5ZGW |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | ndm-1, metallo-beta-lactamase, antibiotic resistent, conformational change, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 26152.05 |
Authors | |
Primary citation | Zhang, H.,Ma, G.,Zhu, Y.,Zeng, L.,Ahmad, A.,Wang, C.,Pang, B.,Fang, H.,Zhao, L.,Hao, Q. Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62:-, 2018 Cited by PubMed: 30150473DOI: 10.1128/AAC.01579-18 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
Download full validation report