5ZGG
NMR structure of p75NTR transmembrane domain in complex with NSC49652
Summary for 5ZGG
| Entry DOI | 10.2210/pdb5zgg/pdb |
| NMR Information | BMRB: 36172 |
| Descriptor | Tumor necrosis factor receptor superfamily member 16, (2E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one (2 entities in total) |
| Functional Keywords | transmembrane, complex, membrane protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 7655.94 |
| Authors | Lin, Z.,Ibanez, C. (deposition date: 2018-03-08, release date: 2019-03-13, Last modification date: 2019-09-25) |
| Primary citation | Goh, E.T.H.,Lin, Z.,Ahn, B.Y.,Lopes-Rodrigues, V.,Dang, N.H.,Salim, S.,Berger, B.,Dymock, B.,Senger, D.L.,Ibanez, C.F. A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTRInduces Melanoma Cell Death and Reduces Tumor Growth. Cell Chem Biol, 25:1485-1494.e5, 2018 Cited by PubMed: 30293939DOI: 10.1016/j.chembiol.2018.09.007 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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