5ZDR

Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative

Summary for 5ZDR

Entry DOI	10.2210/pdb5zdr/pdb
Descriptor	Alternative oxidase, mitochondrial, FE (III) ION, HYDROXIDE ION, ... (5 entities in total)
Functional Keywords	membrane bound diiron protein, oxidoreductase, membrane protein
Biological source	Trypanosoma brucei brucei
Total number of polymer chains	4
Total formula weight	152499.35
Authors	Shiba, T.,Inaoka, D.K.,Takahashi, G.,Tsuge, C.,Kido, Y.,Young, L.,Ueda, S.,Balogun, E.O.,Nara, T.,Honma, T.,Tanaka, A.,Inoue, M.,Saimoto, H.,Harada, S.,Moore, A.L.,Kita, K. (deposition date: 2018-02-23, release date: 2019-02-27, Last modification date: 2023-11-22)
Primary citation	Shiba, T.,Inaoka, D.K.,Takahashi, G.,Tsuge, C.,Kido, Y.,Young, L.,Ueda, S.,Balogun, E.O.,Nara, T.,Honma, T.,Tanaka, A.,Inoue, M.,Saimoto, H.,Harada, S.,Moore, A.L.,Kita, K. Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860:375-382, 2019 Cited by PubMed: 30910528 DOI: 10.1016/j.bbabio.2019.03.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation