5ZAL
Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate
Summary for 5ZAL
Entry DOI | 10.2210/pdb5zal/pdb |
EMDB information | 6905 |
Descriptor | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) (3 entities in total) |
Functional Keywords | dicer, trbp, cryo-em, rna interference, protein binding, hydrolase-protein binding-rna complex, hydrolase/protein binding/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 281408.43 |
Authors | Liu, Z.,Wang, J.,Cheng, H.,Ke, X.,Sun, L.,Zhang, Q.C.,Wang, H.-W. (deposition date: 2018-02-07, release date: 2018-05-09, Last modification date: 2020-08-05) |
Primary citation | Liu, Z.,Wang, J.,Cheng, H.,Ke, X.,Sun, L.,Zhang, Q.C.,Wang, H.W. Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173:1191-1203.e12, 2018 Cited by PubMed: 29706542DOI: 10.1016/j.cell.2018.03.080 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
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