5ZA2
Fox-4 beta-lactamase complexed with avibactam
Summary for 5ZA2
| Entry DOI | 10.2210/pdb5za2/pdb |
| Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | beta-lactamase drug resistance, hydrolase |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 2 |
| Total formula weight | 77306.15 |
| Authors | Nukaga, M.,Hoshino, T.,Papp-Wallace, K.M.,Bonomo, R.A. (deposition date: 2018-02-06, release date: 2018-03-07, Last modification date: 2018-05-09) |
| Primary citation | Nukaga, M.,Papp-Wallace, K.M.,Hoshino, T.,Lefurgy, S.T.,Bethel, C.R.,Barnes, M.D.,Zeiser, E.T.,Johnson, J.K.,Bonomo, R.A. Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam Antimicrob. Agents Chemother., 62:-, 2018 Cited by PubMed: 29439972DOI: 10.1128/AAC.02371-17 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.503 Å) |
Structure validation
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