5Z66

Structure of periplasmic trehalase from Diamondback moth gut bacteria complexed with validoxylamine

Summary for 5Z66

Entry DOI	10.2210/pdb5z66/pdb
Descriptor	Periplasmic trehalase, SULFATE ION, (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, ... (5 entities in total)
Functional Keywords	trehalase from insect gut bacterium, inhibitor validoxylamine-bound structure, hydrolase
Biological source	Enterobacter cloacae
Total number of polymer chains	1
Total formula weight	64363.47
Authors	Harne, S.R.,Adhav, A.S.,Joshi, R.S.,Gayathri, P. (deposition date: 2018-01-22, release date: 2019-01-23, Last modification date: 2023-11-22)
Primary citation	Adhav, A.,Harne, S.,Bhide, A.,Giri, A.,Gayathri, P.,Joshi, R. Mechanistic insights into enzymatic catalysis by trehalase from the insect gut endosymbiont Enterobacter cloacae. Febs J., 286:1700-1716, 2019 Cited by PubMed: 30657252 DOI: 10.1111/febs.14760 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation