5Z4O
Bacterial GyrB ATPase domain in complex with a chemical fragment
Summary for 5Z4O
Entry DOI | 10.2210/pdb5z4o/pdb |
Descriptor | DNA gyrase subunit B, 4-phenoxyphenol, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | dna topoisomerase, antibacterial, drug target, fragment-base lead discovery, isomerase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 2 |
Total formula weight | 46391.37 |
Authors | |
Primary citation | Huang, X.,Guo, J.,Liu, Q.,Gu, Q.,Xu, J.,Zhou, H. Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes Medchemcomm, 9:1619-1629, 2018 Cited by PubMed: 30429968DOI: 10.1039/c8md00148k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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