5YWK

Crystal structure of Arabidopsis thaliana HPPD complexed with Benquitrione-Methyl

5YWK の概要

• エントリーDOI: 10.2210/pdb5ywk/pdb
• 関連するPDBエントリー: 5DHW
• 分子名称: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-3-(2-methylphenyl)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione, ... (4 entities in total)
• 機能のキーワード: 4-hydroxyphenylpyruvate dioxygenase, herbicide, drug discovery, oxidoreductase
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98702.41

構造登録者

Yang, W.C.,Lin, H.Y. (登録日: 2017-11-29, 公開日: 2019-01-16, 最終更新日: 2023-11-22)

• 主引用文献: Qu, R.Y.,Nan, J.X.,Yan, Y.C.,Chen, Q.,Ndikuryayo, F.,Wei, X.F.,Yang, W.C.,Lin, H.Y.,Yang, G.F.; Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide.; J.Agric.Food Chem., 69:459-473, 2021; PubMed: 33395281; DOI: 10.1021/acs.jafc.0c03844

実験手法

X-RAY DIFFRACTION (2.804 Å)