5YVM

Crystal Structure of the archaeal halo-thermophilic Red Sea brine pool alcohol dehydrogenase ADH/D1 bound to NZQ

Summary for 5YVM

Entry DOI	10.2210/pdb5yvm/pdb
Descriptor	alcohol dehydrogenase, MANGANESE (II) ION, 5,6-DIHYDROXY-NADP, ... (4 entities in total)
Functional Keywords	protein-cofactor complex, dehydrogenase, nzq, 5s6s-nadph(oh)2, halophilic, thermophilic, oxidoreductase
Biological source	candidate divison MSBL1 archaeon SCGC-AAA259E19
Total number of polymer chains	1
Total formula weight	45203.25
Authors	Groetzinger, S.W.,Strillinger, E.,Frank, A.,Eppinger, J.,Groll, M.,Arold, S.T. (deposition date: 2017-11-26, release date: 2017-12-27, Last modification date: 2023-11-22)
Primary citation	Groetzinger, S.W.,Karan, R.,Strillinger, E.,Bader, S.,Frank, A.,Al Rowaihi, I.S.,Akal, A.,Wackerow, W.,Archer, J.A.,Rueping, M.,Weuster-Botz, D.,Groll, M.,Eppinger, J.,Arold, S.T. Identification and Experimental Characterization of an Extremophilic Brine Pool Alcohol Dehydrogenase from Single Amplified Genomes ACS Chem. Biol., 13:161-170, 2018 Cited by PubMed: 29188989 DOI: 10.1021/acschembio.7b00792 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation