5YR1

Crystal Structure of Cypovirus Polyhedra R13A/E73C/Y83C/S193C/A194C Mutant

5YR1 の概要

• エントリーDOI: 10.2210/pdb5yr1/pdb
• 分子名称: Polyhedrin, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: in vivo protein crystal, polyhedra, viral protein, disulfide bond
• 由来する生物種: Bombyx mori cytoplasmic polyhedrosis virus (BmCPV)
• 細胞内の位置: Host cytoplasm: P11041
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28740.89

構造登録者

Negishi, H.,Abe, S.,Yamashita, K.,Hirata, K.,Niwase, K.,Boudes, M.,Coulibaly, F.,Mori, H.,Ueno, T. (登録日: 2017-11-08, 公開日: 2018-02-21, 最終更新日: 2024-10-16)

主引用文献

Negishi, H.,Abe, S.,Yamashita, K.,Hirata, K.,Niwase, K.,Boudes, M.,Coulibaly, F.,Mori, H.,Ueno, T.
Supramolecular protein cages constructed from a crystalline protein matrix
Chem. Commun. (Camb.), 54:1988-1991, 2018

PubMed Abstract: Protein crystals are formed via ordered arrangements of proteins, which assemble to form supramolecular structures. Here, we show a method for the assembly of supramolecular protein cages within a crystalline environment. The cages are stabilized by covalent cross-linking allowing their release via dissolution of the crystal. The high stability of the desiccated protein crystals allows cages to be constructed.

PubMed: 29405208
DOI: 10.1039/c7cc08689j

実験手法

X-RAY DIFFRACTION (1.72 Å)