5YNI

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG

Summary for 5YNI

Descriptornsp16 protein, nsp10 protein, S-ADENOSYLMETHIONINE, ... (6 entities in total)
Functional Keywordsinhibitor, complex, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
Total number of polymer chains2
Total molecular weight49973.19
Authors
Wei, S.M.,Yang, L.,Ke, Z.H.,Chen, Y.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05)
Primary citation
Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Yang, Z.Z.,Chen, Y.,Guo, D.Y.,Fan, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.07 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2252 0.2% 0.6% 6.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution