5YN6

Crystal structure of MERS-CoV nsp10/nsp16 complex bound to SAM

Summary for 5YN6

Descriptornsp16 protein, nsp10 protein, S-ADENOSYLMETHIONINE, ... (5 entities in total)
Functional Keywordscomplex, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
Total number of polymer chains2
Total molecular weight49169.75
Authors
Wei, S.M.,Yang, L.,Ke, Z.H.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05)
Primary citation
Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Che, Y.,Yang, Z.Z.,Guo, D.Y.,Fan, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.947 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2162 0.3% 0.9% 11.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5yn6
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Molmil generated image of 5yn6
rotated about x axis by 90°
Molmil generated image of 5yn6
rotated about y axis by 90°