5YN5

Crystal structure of MERS-CoV nsp10/nsp16 complex

Summary for 5YN5

Descriptornsp16 protein, nsp10 protein, ZINC ION, ... (4 entities in total)
Functional Keywords2'-o-mtase, transferase
Biological sourceHuman betacoronavirus 2c EMC/2012
Total number of polymer chains2
Total molecular weight48771.31
Authors
Wei, S.M.,Yang, L.,Ke, Z.H.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05)
Primary citation
Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Yang, Z.Z.,Chen, Y.,Guo, D.Y.,Fan, C.P.
Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.96 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2063 0.2% 1.8% 11.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution