5YFY

Plasmodium vivax SHMT bound with PLP-glycine and GS625

5YFY の概要

• エントリーDOI: 10.2210/pdb5yfy/pdb
• 分子名称: Serine hydroxymethyltransferase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], 1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]piperidine-4-carboxylic acid, ... (5 entities in total)
• 機能のキーワード: alpha and beta protein, transferase, methyltransferase activity, inhibitor, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Plasmodium vivax
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 150055.46

構造登録者

Chitnumsub, P.,Jaruwat, A.,Leartsakulpanich, U.,Schwertz, G.,Diederich, F. (登録日: 2017-09-22, 公開日: 2018-09-26, 最終更新日: 2023-11-22)

• 主引用文献: Chitnumsub, P.,Jaruwat, A.; to be published; to be published,

実験手法

X-RAY DIFFRACTION (2.3 Å)