5YE3

Crystal structure of the complex of di-acetylated histone H4 and 2A7D9 Fab fragment

Summary for 5YE3

• Entry DOI: 10.2210/pdb5ye3/pdb
• Descriptor: 2A7D9 VH CH1 chain, 2A7D9 L chain, di-acetylated histone H4, ... (4 entities in total)
• Functional Keywords: antibody, histone, complex, nuclear protein
• Biological source: Mus musculus; More
• Total number of polymer chains: 3
• Total formula weight: 47331.73

Authors

Matsuda, T.,Ito, T.,Wakamori, M.,Umehara, T. (deposition date: 2017-09-15, release date: 2018-08-22, Last modification date: 2023-11-22)

• Primary citation: Handoko, L.,Kaczkowski, B.,Hon, C.C.,Lizio, M.,Wakamori, M.,Matsuda, T.,Ito, T.,Jeyamohan, P.,Sato, Y.,Sakamoto, K.,Yokoyama, S.,Kimura, H.,Minoda, A.,Umehara, T.; JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.; Epigenetics, 13:410-431, 2018; PubMed: 30080437; DOI: 10.1080/15592294.2018.1469891

Experimental method

X-RAY DIFFRACTION (1.7 Å)