5YDZ
structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 1
Summary for 5YDZ
Entry DOI | 10.2210/pdb5ydz/pdb |
EMDB information | 6823 |
Descriptor | mammalian endo-lysosomal TRPML1 channel (1 entity in total) |
Functional Keywords | mtrpml1, mucolipidosis type iv, structual comparisons, combined regulation mechanism, membrane protein |
Biological source | Mus musculus (Mouse) |
Cellular location | Late endosome membrane ; Multi-pass membrane protein : Q99J21 |
Total number of polymer chains | 4 |
Total formula weight | 262294.47 |
Authors | |
Primary citation | Zhang, S.,Li, N.,Zeng, W.,Gao, N.,Yang, M. Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8:834-847, 2017 Cited by PubMed: 28936784DOI: 10.1007/s13238-017-0476-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.8 Å) |
Structure validation
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