5Y1K
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide
Summary for 5Y1K
Entry DOI | 10.2210/pdb5y1k/pdb |
Descriptor | M1 family aminopeptidase, ZINC ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | m1-class aminopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 107296.14 |
Authors | Marapaka, A.K.,Zhang, Y.,Addlagatta, A. (deposition date: 2017-07-20, release date: 2018-08-01, Last modification date: 2023-11-22) |
Primary citation | Marapaka, A.K.,Sankoju, P.,Zhang, G.,Ding, Y.,Ma, C.,Pillalamarri, V.,Sudhakar, P.,Reddi, B.,Sijwali, P.S.,Zhang, Y.,Addlagatta, A. Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization Chin.Chem.Lett., 33:2550-2554, 2022 Cited by DOI: 10.1016/j.cclet.2021.09.102PDB entries with the same primary citation |
Experimental method |
Structure validation
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