5Y0A

Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree

Summary for 5Y0A

• Entry DOI: 10.2210/pdb5y0a/pdb
• EMDB information: 6793
• Descriptor: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain (3 entities in total)
• Functional Keywords: virus, antibody, complex, virus-immune system complex, icosahedral virus, virus/immune system
• Biological source: Zika virus (strain Mr 766) (ZIKV); More
• Total number of polymer chains: 9
• Total formula weight: 211245.54

Authors

Wang, J.Q.,Lok, S.M. (deposition date: 2017-07-15, release date: 2017-10-04, Last modification date: 2024-03-27)

• Primary citation: Wang, J.,Bardelli, M.,Espinosa, D.A.,Pedotti, M.,Ng, T.S.,Bianchi, S.,Simonelli, L.,Lim, E.X.Y.,Foglierini, M.,Zatta, F.,Jaconi, S.,Beltramello, M.,Cameroni, E.,Fibriansah, G.,Shi, J.,Barca, T.,Pagani, I.,Rubio, A.,Broccoli, V.,Vicenzi, E.,Graham, V.,Pullan, S.,Dowall, S.,Hewson, R.,Jurt, S.,Zerbe, O.,Stettler, K.,Lanzavecchia, A.,Sallusto, F.,Cavalli, A.,Harris, E.,Lok, S.M.,Varani, L.,Corti, D.; A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.; Cell, 171:229-241.e15, 2017; PubMed: 28938115; DOI: 10.1016/j.cell.2017.09.002

Experimental method

ELECTRON MICROSCOPY (22 Å)