5XWV
Substrate-bound Structure of a Ketoreductase from the Second Module of the amphotericin Polyketide Synthases
Summary for 5XWV
Entry DOI | 10.2210/pdb5xwv/pdb |
Descriptor | AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate, ... (4 entities in total) |
Functional Keywords | modular polyketide synthease, ketoreductase, oxidoreductase |
Biological source | Streptomyces nodosus |
Total number of polymer chains | 2 |
Total formula weight | 105121.23 |
Authors | |
Primary citation | Liu, C.,Yuan, M.,Xu, X.,Wang, L.,Keatinge-Clay, A.T.,Deng, Z.,Lin, S.,Zheng, J. Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase. J. Struct. Biol., 203:135-141, 2018 Cited by PubMed: 29626512DOI: 10.1016/j.jsb.2018.04.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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