5XVK

Crystal structure of mouse Nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl Nicotinamide (MNA)

5XVK の概要

• エントリーDOI: 10.2210/pdb5xvk/pdb
• 分子名称: Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 3-carbamoyl-1-methylpyridin-1-ium, ... (5 entities in total)
• 機能のキーワード: nnmt, mna, ternary complex, feedback inhibition, t2d, transferase
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64735.46

構造登録者

Swaminathan, S.,Birudukota, S.,Thakur, M.K.,Parveen, R.,Kandan, S.,Kannt, A.,Gosu, R. (登録日: 2017-06-28, 公開日: 2017-08-02, 最終更新日: 2023-11-22)

• 主引用文献: Swaminathan, S.,Birudukota, S.,Thakur, M.K.,Parveen, R.,Kandan, S.,Juluri, S.,Shaik, S.,Anand, N.N.,Burri, R.R.,Kristam, R.,Hallur, M.S.,Rajagopal, S.,Schreuder, H.,Langer, T.,Rudolph, C.,Ruf, S.,Dhakshinamoorthy, S.,Gosu, R.,Kannt, A.; Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide; Biochem. Biophys. Res. Commun., 491:416-422, 2017; PubMed: 28720493; DOI: 10.1016/j.bbrc.2017.07.087

実験手法

X-RAY DIFFRACTION (1.88 Å)