5XUV

Crystal structure of DNA duplex containing 4-thiothymine-2Ag(I)-4-thiothymine base pairs

Summary for 5XUV

• Entry DOI: 10.2210/pdb5xuv/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*(8RO)P*(8RO)P*TP*CP*GP*CP*G)-3'), SILVER ION, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: dna, metallo-base pair, silver
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 7818.69

Authors

Kondo, J.,Sugawara, T.,Saneyoshi, H.,Ono, A. (deposition date: 2017-06-26, release date: 2017-09-20, Last modification date: 2023-11-22)

Primary citation

Kondo, J.,Sugawara, T.,Saneyoshi, H.,Ono, A.
Crystal structure of a DNA duplex containing four Ag(i) ions in consecutive dinuclear Ag(i)-mediated base pairs: 4-thiothymine-2Ag(i)-4-thiothymine
Chem. Commun. (Camb.), 53:11747-11750, 2017

PubMed Abstract: Herein, we determined a high-resolution crystal structure of a B-form DNA duplex containing consecutive dinuclear metal ion-mediated base pairs, namely, 4-thiothymine-2Ag(i)-4-thiothymine (S-2Ag(i)-S), and four Ag(i) ions form a rectangular network and the distances between the Ag(i) ions are 2.8-3.2 Å, which may indicate the existence of metallophilic attractions.

PubMed: 28991300
DOI: 10.1039/c7cc06153f

Experimental method

X-RAY DIFFRACTION (1.9 Å)